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林 乃君
專任教師
職稱 副教授
姓名 林 乃君
聯絡電話 02-33663840
研究室電話 02-33662428
電子郵件 nlin@ntu.edu.tw
研究專長 微生物學, 分子生物學, 微生物與植物之交互作用
授課領域 普通微生物學
普通微生物學實驗
環境微生物學
環境微生物學實驗
分子生物學
農化研究及實驗法一、二、三 環境生物技術理論與應用
微生物學特論
生物技術核心實驗 (生技學程)
分子生物與細胞學 (生技學程)農用生物製劑 (植微系)
植物病原交互作用分子機制 (植病所)
進階微生物學 (植病所)
研究室網站 http://lab.ac.ntu.edu.tw/NCLin/homepage.htm
國家 學校名稱 系所 學位
美國 康乃爾大學 植物病理研究所 博士
臺灣 國立臺灣大學 植物病蟲害研究所植物病理組 碩士
臺灣 國立臺灣大學 植物病蟲害學系植物病理組 學士
Fouts, D. E., Abramovitch, R. B., Alfano, J. R., Baldo, A. M., Buell, C. R., Cartinhour, S., Chatterjee, A. K., D'Ascenzo, M., Gwinn, M. L., Lazarowitz, S. G., Lin, N.-C., Martin, G. B., Rehm, A. H., Schneider, D. J., van Dijk, K., Tang, X., and Collmer, A. 2002. Genomewide identification of Pseudomonas syringae pv. tomato DC3000 promoters controlled by the HrpL alternative sigma factor. Proc. Natl. Acad. Sci. USA 99: 2275-2280.
 
Kim, Y. J., Lin, N.-C., and Martin, G. B. 2002. Two distinct Pseudomonas effector proteins interact with the Pto kinase and activate plant immunity. Cell 109: 589-598.
 
Lin, N.-C., and Martin, G. B. 2005. An avrPto/avrPtoB mutant of Pseudomonas syringae pv. tomato DC3000 does not elicit Pto-mediated resistance and is less virulent on tomato. Mol. Plant-Microbe Interact. 18: 43-51.
 
Lin, N.-C., Abramovitch, R. B., Kim, Y. J., Martin, G. B. 2006. Diverse AvrPtoB homologs from several Pseudomonas syringae pathovars elicit Pto-dependent resistance and have similar virulence activities. Appl. Environ. Microbiol. 72: 702-712.
 
He, P., Shan, L., Lin, N.-C., Martin, G. B., Kemmerling, B., Nürnberger, T., Sheen, J. 2006. Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity. Cell 125: 563-575.
 
Wei, C. F., Kvitko, B. H., Shimizu, R., Crabill, E., Alfano, J. R., Lin, N.-C., Martin, G. B., Huang, H. C., Collmer, A. 2007. A Pseudomonas syringae pv. tomato DC3000 mutant lacking the type III effector HopQ1-1 is able to cause disease in the model plant Nicotiana benthamiana. Plant J. 51:32-46.
 
Lin, N.-C., and Martin, G. B. 2007. Pto- and Prf-mediated recognition of AvrPto and AvrPtoB restricts the ability of diverse Pseudomonas syringae pathovars to infect tomato. Mol Plant-Microbe Interact. 20:806-815.
 
Hsieh,  F. C., Chen, C. T., Weng, Y. T., Peng, S. S., Chen, Y. C., Huang, L. Y., Hu, H. T., Wu, Y. L., Lin, N. C.,* and Wu, W. F. 2011. Stepwise activity of ClpY (HslU) mutants in the processive degradation of Escherichia coli ClpYQ (HslUV) protease substrates. J. Bacteriol. 193:5465-5476.
 
Hwang, S. G., Lin,  N. C., Hsiao, Y. Y., Kuo, C. H., Chang, P. F., Deng, W. L., Chiang, M. H., Shen, H. L., Chen, C. Y., and Cheng, W. H. 2012. The Arabidopsis short-chain dehydrogenase/reductase 3, an abscisic acid deficient 2 homolog, is involved in plant defense responses but not in ABA biosynthesis. Plant Physiol. Biochem. 51: 63-73.

Wang, L.Y., Lin, S. S., Hung, T. H., Li, T. K., Lin, N. C., and Shen, T. L. 2012. Multiple domains of the tobacco mosaic virus p126 protein can independently suppress local and systemic RNA silencing. Mol. Plant Microbe Interact. 25: 648-657.

Haapalainen, M., Mosorin, H., Dorati, F., Wu, R.-F., Roine, E., Taira, S., Nissinen, R., Mattinen, L., Jackson, R., Pirhonen, M., and Lin, N.-C*. (2012) Hcp2, a secreted protein of the phytopathogen Pseudomonas syringae pv. tomato DC3000, is required for competitive fitness against bacteria and yeasts. J. Bacteriol. 194: 4810-4822.

Chien, C.-F., Mathieu, J., Hsu, C.-H., Boyle, P., Martin, G. B. and Lin, N.-C*. (2013) Nonhost resistance of tomato to the bean pathogen Pseudomonas syringae pv. syringae B728a is due to a defective E3 ubiquitin ligase domain in AvrPtoBB728a. Mol. Plant-Microbe Interact. 26: 387-397.

Peng, Y.-H., Lai, Y.-C., Lin, N.-C., Liu, Y.-Z., Liu, Y.-T., and Shih, Y.-H. (2014) Degradation of polyurethane by bacterium isolated from soil and assessment of polyurethanolytic activity of Pseudomonas putida strain. Environ. Sci. Pollut. Res. 21:9529–9537.
 
 
Kim, Y.-J. Lin, N.-C., and Martin, G. (July, 2001). Pseudomonas effector protein AvrPto2 interacts with Pto kinase and elicits disease resistance in tomato plant expressing Pto. 10th International Congress on Molecular Plant-Microbe Interaction, Madison, WI, USA.

Lin, N.-C., Kim, Y.-J., Tsiamis, G., Mansfield, J. W. and Martin, G. B. (July, 2001). AvrPto2 is a virulence factor that is widely conserved among Pseudomonas strains. 10th International Congress on Molecular Plant-Microbe Interaction, Madison, WI, USA.

Ramos A. R. Oh, H.-S., Lin, N.-C., Deng, W.-L., Collmer, A. (July, 2001). Characterization of two native plasmids in the tomato and Arabidopsis pathogen Psuedomoans syrinage pv. tomato DC3000. 10th International Congress on Molecular Plant-Microbe Interaction, Madison, WI, USA. 

Lin, N.-C., and Martin, G. B. (July, 2005) Recognition of AvrPto and AvrPtoB by Pto in tomato plays a role in host specificity of Pseudomonas syringae pathovars. 12th International Congress on Molecular Plant-Microbe Interaction, Cancun, Mexico.

Lin, N.-C., and Martin, G. B. (July, 2007) An AvrPtoB homolog in Pseudomonas syringae pv. syringae B728a elicits immunity in tomato cultivar that do not have the Pto gene. 13th International Congress on Molecular Plant-Microbe Interaction, Sorrento, Italy.

Jessica Yu, Shao-Wen Chen, Ching-Fang Chien, Yuan-Yu Wang, Zu-Fen Wu and Nai-Chun Lin (July, 2008) Functional analysis of type III effectors in Pseudomonas syringae pv. syringae strain B728a. XII International Congress of Bacteriology and Applied Microbiology, Istanbul, Turkey.

Ching-Fang Chien and Nai-Chun Lin (July, 2009) Identification of domains required for AvrPtoBB728a interactions with Pto family members from Solanum lycopersicum and its function to trigger defense responses in tomato VFNT cherry. 14th International Congress on Molecular Plant-Microbe Interaction, Quebec city, Canada.

Yuan-Yu Wang, Ru-Feng Wu, and Nai-Chun Lin (July, 2009) Characterization of type VI secretion systems in Pseudomonas syringae pv. tomato DC3000. 14th International Congress on Molecular Plant-Microbe Interaction, Quebec city, Canada.

Ru-Fen Wu and Nai-Chun Lin (August, 2010) Characterization of the expression and functions of type VI secretion systems from Pseudomonas syringae pv. tomato DC3000.  The 8th International Conference on Pseudomonas syringae and related pathogens, Oxford, UK (31th Aug-3rd Sept, 2010).

Ching-Fang Chien, Chun-Hua Hsu and Nai-Chun Lin. (August, 2010) AvrPtoBB728a functions differently from AvrPtoB to elicit Pto-independent resistance in tomato. The 8th International Conference on Pseudomonas syringae and related pathogens, Oxford, UK (31th Aug-3rd Sept, 2010).

Minna Haapalainen, Hanna Mosorin, Federico Dorati, Ru-Fen Wu, Elina Roine, Suvi Taira2, Riitta Nissinen, Laura Mattinen, Robert Jackson, Minna Pirhonen, Nai-Chun Lin (July, 2012) Hcp2, a secreted protein of the phytopathogen Pseudomonas syringae pv. tomato DC3000, is required for competitive fitness against bacteria and yeasts. 15th International Congress on Molecular Plant-Microbe Interaction, Kyoto, Japan.

Nai-Tan Hsu, Cheng-Yin Liu, Yung-Chun Wang, Chih-Teng Hsu, Yi-Han How and Nai-Chun Lin (July, 2012) The HSI-II gene cluster in Pseudomonas syringae pv. tomato DC3000 encodes a functional type VI secretion system, which is required for growth fitness in tomato and interbacterial competition. 15th International Congress on Molecular Plant-Microbe Interaction, Kyoto, Japan.

Ching-Fang Chien, Cheng-Ying Liu and Nai-Chun Li (Sept, 2013) HSI-II gene cluster of Pseudomonas syringae pv. tomato DC3000 encodes a functional type VI secretion system and is regulated by a global regulator GacA. 14th International Conference on Pseudomonas. 

Lin-Jie Shu, Nai-Chun Lin, Chia-Lin Chung (July, 2014) Validation of the role of NPR1-like genes in defense against anthracnose in strawberry and development of virus-induced gene silencing technique. 16th International Congress on Molecular Plant-Microbe Interaction, Rhodes Island, Greece.

Ching-Fang Chien, Nai-Tan Hsu and Nai-Chun Lin (July, 2014) Systematic analysis of the Hcp secretion island (HSI)-II revealed that both Sfa2 and RpoN are required for the expression of hcp2 gene in Pseudomonas syringe pv. tomato DC3000. 16th International Congress on Molecular Plant-Microbe Interaction, Rhodes Island, Greece

Chien, C.-F and Lin, N.-C. 2015. Hcp secretion island (HSI)-II encodes the only type VI secretion system for interbacterial competition in Pseudomonas syringe pv. tomato DC3000. The 9th International Conference on Pseudomonas syringae pathovars and related pathogens. Malaga,Spain.

Lin, N.-C. and Chen, K.Y. 2015. PSPTO_5415 and PSPTO_5436 encode two major VgrG homologs involoved in interbacterial competition ability of Pseudomonas syringae pv. Tomato DC3000. The 9th International Conference on Pseudomonas syringae pathovars and related pathogens. Malaga,Spain.

Lu, Y.-Y. and Lin, N.-C. 2015. Characterization of PSPTO_0281 gene in phytopathogenic Pseudomonas syringae pv. tomato DC3000. The 9th International Conference on Pseudomonas syringae pathovars and related pathogens. Malaga,Spain.
Yeh, I.-C., Chung, R.-S. and Lin, N.-C. 2015. Effect of silicon supplement on celery wilt. The 6th International Conference of Clinical Plant Science 2015. Tokyo, Japan.

Liu, Y.-T., and Lin, N.-C. 2015. Development of strategies to alleviate succession cropping obstacle of celery in Taiwan. The 6th International Conference of Clinical Plant Science 2015. Tokyo, Japan.
Devarenne, T. P., Riely, B. K., Lin, N.-C., Young, J.-K., Cohn, J., Mysore, K., Charkravarthy, S., Bogdanove, A. J., D’Ascenzo, M., Debbie, P., Tuori, B., and Martin, G. B. 2002. Recognition of Pseudomonas effector proteins by tomato and profiling of plant gene expression changes that occur during plant-pathogen interactions. 58-63 in: Biology of Plant-Microbe Interactions Volume 3. eds. S. A. Leong, C. Allen, and E. W. Triplett. International Society for Molecular Plant-Microbe interaction. St. Paul, Minnesota.
 
Abramovitch, R. B., Anderson, J. C., Lin, N.-C., and Martin, G. B. 2004. The role of Pseudomonas type III effectors AvrPto and AvrPtoB as modulators of plant disease susceptibility and immunity. 180-183 in: Biology of plant-microbe interactions, Volume 4: Molecular plant-microbe interactions: new bridges between past and future. eds. I.  Tikhonovich, B. Lugtenberg, and N. Provorov. International Society for Molecular Plant-Microbe interaction. St. Paul, Minnesota.
 
Chang, Y. C., and Lin, N.-C. 2009. Chapter 3. Genetic manipulation. Pages 63-96 in: Introduction to biotechnology. eds. C. P. Lin, R. F. Liou, R. H. Chuang, S. T. Ding, and H. S. Lee. Farseeing publishing group. Tapei, Taiwan. (in Chinese)